| 产品详情 |
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| Product Name | L-Leucyl-L-Leucine methyl ester (hydrochloride) |
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| Description | Purity >95%. L-Leucyl-L-Leucine methyl ester (LLME) is a lysosomal condensation product that has been reported to be cytotoxic towards natural killer cells and CD4+ and CD8+ T lymphocytes without affecting helper T cells and B cells. It has also been shown to induce death of monocytes, polymorphonuclear leukocytes, and myeloid tumor cells. Upon entry into cells via receptor-mediated endocytosis, LLME undergoes a condensation process catalyzed by dipeptidyl peptidase I (DPPI) in lysosomes. This condensation leads to lysosomal rupture and DNA fragmentation in DPPI-expressing immune cells such as cytotoxic T cells and natural killer cells. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | L-leucyl-L-leucine, methyl ester, monohydrochloride, LLME, LLOMe |
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| Gene, Accession, CAS # | CAS: 6491-83-4 |
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| Catalog # | LS-H8492 |
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| Order / More Info | L-Leucyl-L-Leucine methyl ester (hydrochloride) from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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