| 产品详情 |
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| Product Name | Fas Ligand (TNF Superfamily, Member 6) (FASL) (Active) protein |
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| Description | Fas and Fas Ligand (FasL) belong to the TNF superfamily and are type I and type II transmembrane proteins, respectively. Binding of FasL to Fas triggers apoptosis in Fas-bearing cells. The mechanism of apoptosis involves recruitment of pro-caspase 8 through an adaptor molecule called FADD followed by processing of the pro-enzyme to active forms. These active caspases then cleave various cellular substrates leading to the eventual cell death. sFasR is capable of inhibiting FasL-induced apoptosis by acting as a decoy receptor that serves as a sink for FasL. The full length Fas (receptor) is a 319 amino acid type I transmembrane protein, which contains a 157 amino acid extracellular domain, a 17 amino acid transmembrane domain, and 145 amino acid cytoplasmic domain. Alternative Names: Apo I Ligand protein, CD95L protein, TNFSF6 protein, soluble Fas Ligand protein, APTL protein, sFASL protein |
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| Size | 10 µg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | fasl|FASL|FASLG|FAS|TNFRSF6|zgc:162027|TNFSF6|ALPS1B|APT1LG1|APTL|CD178|CD95-L|CD95L|Fas-L|Faslg|Tnfsf6|gld|Apt1Lg1|Fasl |
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| Gene, Accession, CAS # | Gene ID: 356 |
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| Catalog # | ABIN935363 |
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| Order / More Info | Fas Ligand (TNF Superfamily, Member 6) (FASL) (Active) protein from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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