| 产品详情 |
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| Antigenic Specificity | BAFF |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blot: 0.5-2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | BAFF Polyclonal Antibody. Membrane-bound BAFF is processed and secreted through the action of a protease whose specificity matches that of the furin family of proprotein convertases. Secreted BLyS/BAFF/THANK acts as a potent B cell growth factor. This protein is expressed abundantly in peripheral blood lymphocytes, specifically in monocytes and macrophages. Its regulation is upregulated by interferon gamma. Overexpression of BLyS/BAFF in transgenic mice lead to increased numbers of mature B and effector T cells. These mice also develop autoimmune -like symptoms, such as, high levels of rheumatoid factors, anti-DNA autoantibodies, etc. (2). Recently, two receptors for BLyS/BAFF have been identified and termed as BCMA and TACI (1). |
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| Immunogen | n/a |
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| Other Names | BAFF, BLYS, DTL, TALL-1, TALL1, THANK, TNFSF20, ZTNF4, TNFSF13B |
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| Gene, Accession # | Entrez: 10673, 24099; Uniprot: Q9WU72, Q9Y275 |
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| Catalog # | PA1-41266 |
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| Price | |
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| Order / More Info | BAFF Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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