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| Product Name | Recombinant Rat Fibroblast growth factor 23 |
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| Description | 25-251aa; Full Length. MW: 29.6kD. Purity >90% as determined by SDS-PAGE. Regulator of phosphate homeostasis. Inhibits renal tubular phosphate transport by reducing SLC34A1 levels. Regulator of vitamin-D metabolism. Negatively regulates osteoblasts differentiation and matrix mineralization. Acts directly on the parathyroid to decrease PTH secretion. Upregulates EGR1 expression in the presence of KL. |
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| Size | 0.01 mg (E-Coli), 0.01 mg (Yeast), 0.05 mg (E-Coli), 0.05 mg (Yeast), 0.1 mg (E-Coli) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [fibroblast growth factor 23; Fibroblast growth factor 23; fibroblast growth factor 23; fibroblast growth factor 23] |
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| Gene, Accession, CAS # | Fgf23, Gene ID: 170583, Accession: NP_570110.1 |
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| Catalog # | MBS1394494 |
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| Order / More Info | Recombinant Rat Fibroblast growth factor 23 from MYBIOSOURCE INC. |
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| Product Specific References | Rattus norvegicus fgf23.Itoh N.Klotho converts canonical FGF receptor into a specific receptor for FGF23.Urakawa I., Yamazaki Y., Shimada T., Iijima K., Hasegawa H., Okawa K., Fujita T., Fukumoto S., Yamashita T.Nature 444:770-774(2006) The parathyroid is a target organ for FGF23 in rats.Ben-Dov I.Z., Galitzer H., Lavi-Moshayoff V., Goetz R., Kuro-o M., Mohammadi M., Sirkis R., Naveh-Many T., Silver J.J. Clin. Invest. 117:4003-4008(2007) |
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