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| Product Name | SMAD5 Recombinant protein |
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| Description | MW: ~82 kDa. Recombinant full-length human SMAD5 was expressed in E. coli cells using an N-terminal GST tag.Scientific Background: SMAD5 is a member of the SMAD family and mediates signaling by the transforming growth factor-beta (TGFbeta) superfamily and related ligands (1). SMAD5 plays a critical role in the signaling pathway by which TGFbeta inhibits the proliferation of human hematopoietic progenitor cells. SMAD5 is up-regulated in gastric epithelial cells during the infection |
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| Size | 0.02 mg, 0.05 mg |
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| Concentration | n/a |
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| Applications | Kinase Assay, Western Blot (WB) |
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| Other Names | [Dwfc; JV5-1; MADH5; DKFZp781C1895; DKFZp781O1323] |
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| Gene, Accession, CAS # | SMAD5, Gene ID: 4090, Accession: NP_005894.3 |
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| Catalog # | MBS515292 |
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| Order / More Info | SMAD5 Recombinant protein from MYBIOSOURCE INC. |
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| Product Specific References | 1. Heldin, C.H. et al: TGF-beta signalling from cell membrane to nucleus through SMAD proteins. Nature, 1997, 390 (6659): 465 -71. 2. Nagasko, T. et al: Up-regulated Smad5 mediates apoptosis of gastric epithelial cells induced by Helicobacter pylori infection. J Biol Chem. 2003 Feb 14;278(7):4821-5. |
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