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| Product Name | ERK5-IN-1 |
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| Description | Potent and selective ERK5 inhibitor; inhibits EGFR-induced ERK5 autophosphorylation (EC50 = 90 nM) and ERK5 enzymatic activity (IC50 = 162 nM). Exhibits at least 30-fold selectivity for ERK5 over LRRK2 in a cell based assay. Also selective for ERK5 over a panel of other kinases. Orally bioavailable. Purity 98%. MW (observed): 638.8 |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 11-Cyclopentyl-2-[[2-ethoxy-4-[[4-(4-methyl-1-piperazinyl)-1-piperidinyl]carbonyl]phenyl]amino]-5,11-dihydro-5-methyl-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one |
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| Gene, Accession, CAS # | CAS: 1435488-37-1 |
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| Catalog # | 5393/50 |
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| Price | |
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| Order / More Info | ERK5-IN-1 from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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