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| Product Name | ARHGDIA, 24-204aa, Human, His tag, E Coli |
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| Description | MW: 22.9 kDa (202aa) confirmed by MALDI-TOF. Purity >95% by SDS-PAGE. Rho GDP-dissociation inhibitor 1, also known ARHGDIA, belong to the RAS gene superfamily encoding small guanine nucleotide exchange (GTP/GDP) factors. Localized to the cytoplasm, ARHGDIA inhibits the dissociation of GDP from Rho proteins, thereby preventing GTP from binding to and subsequently activating Rho proteins. In humans ARHGDIA can be phosphorylated at Ser 101 by p21-activated kinase, an event that inhibits ARHGDIA act |
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| Size | 0.1 mg, 0.5 mg |
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| Concentration | 1 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [Rho GDP-dissociation inhibitor 1; GDIA1; RHOGDI; RHOGDI-1; Rho-GDI alpha] |
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| Gene, Accession, CAS # | ARHGDIA, Gene ID: 396, Accession: NP_004300 |
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| Catalog # | MBS203878 |
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| Order / More Info | ARHGDIA, 24-204aa, Human, His tag, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | DerMardirossian C., et al. (2006) Mol Biol Cell. 17:4760-4768.; Leffers H., et al. (1993) Exp Cell Res. 209:165-174.; |
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