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| Product Name | Recombinant Mouse Interleukin-21 protein (Il21) (Active) |
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| Description | Purity > 95% as determined by SDS-PAGE. MW: 12.7kDa. Partial: 301-412aa (Y340F). tag-Free. Homo sapiens (Human). Transforming growth factor beta 3 (TGFB3) is a member of a TGF -β superfamily which is defined by theirstructural and functional similarities. TGFB3 is secreted as a complex with LAP. This latent form of TGFB3becomes active upon cleavage by plasmin, matrix metalloproteases, thrombospondin -1, and a subset ofintegrins. It binds with high affinity to TGF- β RII, a type II serine/threonine kinase receptor. TGFB3 is involved incell differentiation, embryogenesis and development.It is believed to regulate molecules involved in cellularadhesion and extracellular matrix (ECM) formation during the process of palate development. Without TGF-β3,mammals develop a deformity known as a cleft palate. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Transforming growth factor beta-3; TGFB3; TGF-beta-3; Latency-associated peptide; LAP |
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| Gene, Accession, CAS # | TGFB3, UniProt: P10600 |
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| Catalog # | RPC26851 |
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| Order / More Info | Recombinant Mouse Interleukin-21 protein (Il21) (Active) from BIOMATIK |
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| Product Specific References | n/a |
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