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| Product Name | SOCS3, 1-225aa, Human, His tag, E Coli (Denatured) |
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| Description | MW: 29 kDa (262aa). Purity >90% by SDS-PAGE. SOCS3 is a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of SOCS3 is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. This protein can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the ro |
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| Size | 0.05 mg, 0.25 mg |
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| Concentration | 0.5 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [Suppressor of cytokine signaling 3; CIS3; SSI3; ATOD4; Cish3; SSI-3; SOCS-3; MGC71791] |
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| Gene, Accession, CAS # | SOCS3, Gene ID: 9021, Accession: NP_003946 |
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| Catalog # | MBS205676 |
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| Order / More Info | SOCS3, 1-225aa, Human, His tag, E Coli (Denatured) from MYBIOSOURCE INC. |
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| Product Specific References | McKay BR, Ogborn DI, et al. (2013). Am J Physiol Cell Physiol. 304 (8):C717-28.; Molavi O, Wang P, et al. (2013). Br J Haematol. 161 (3):348-56.; |
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