产品详情 |
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Product Name | L-685,458 |
Description | Purity ~98% (HPLC). Cell-permeable. A potent and selective γ-secretase inhibitor (IC50 = 17 nM). Displays > 50-fold selectivity over a range of aspartyl, serine and cysteine proteases. Exhibits equal potency for inhibition of Aβ40 and Aβ42 peptides (IC50 values are 48 and 67nM respectively in human neuroblastoma cells). |
Size | 250ug |
Concentration | n/a |
Applications | n/a |
Other Names | L-685,458 ((5S)-(tert-Butoxycarbonylamino)-6-phenyl-(4R)-hydroxy-(2R)-benzylhexanoyl)-L-leucyl-L-phenylalaninamide) |
Gene, Accession, CAS # | n/a |
Catalog # | L0145 |
Price | |
Order / More Info | L-685,458 from UNITED STATES BIOLOGICAL |
Product Specific References | n/a |
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