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| Antigenic Specificity | Smad2 (S250) |
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| Clone | 1G2 |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | IgG |
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| Format | Protein A purified |
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| Size | 100ul |
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| Concentration | 1ug/ul |
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| Applications | WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Smad2 (S250) (1G2) Monoclonal Antibody. • Target Background: Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 |
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| Immunogen | Synthetic peptide derived from human Smad2 (S250), around 220-280aa (phospho S250). |
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| Other Names | Phosphorylated, phospho-JV18; MADH2; MADR2; JV18-1; hMAD-2; hSMAD2; Mothers against decapentaplegic homolog 2; MAD homolog 2; Mothers against DPP homolog 2; Mad-related protein 2; SMAD family member 2; SMAD 2; Smad2 |
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| Gene, Accession # | Gene ID: 4087, SwissProt: Q15796 |
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| Catalog # | bsm-52203R |
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| Price | |
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| Order / More Info | Smad2 (S250) Antibody from BIOSS ANTIBODIES |
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| Product Specific References | n/a |
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