| 产品详情 |
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| Antigenic Specificity | SERPINB3/SERPINB4 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Western Blot: 1:500-1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | SERPINB3/SERPINB4 Polyclonal Antibody. Metastasis of a primary tumor to a distant site is determined through signaling cascades that break down interactions between the cell and extracellular matrix proteins. Among the proteins mediating metastasis are serine prote-ases, such as neutrophil elastase. In 1985, Dr. Jim Travis and Dr. R.W. Carrell designated an emerging family of serine protease inhibitors as the serpin fam-ily, which share homology in both primary amino acid sequence and tertiary structure. Serpins contain a stretch of peptide that mimics a true substrate for a corresponding serine protease. Serine proteases bind to this substrate mimic in a 1:1 stoichiometric fashion and become catalytically inactive. Aberrant ex-pression of |
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| Immunogen | n/a |
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| Other Names | Serpin B3; Protein T4-A; Squamous cell carcinoma antigen 1; SCCA-1; SERPINB3; SCCA; SCCA1; Serpin B4; Leupin; Peptidase inhibitor 11; PI-11; Squamous cell carcinoma antigen 2; SCCA-2; SERPINB4; PI11; SCCA2 |
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| Gene, Accession # | Entrez: 20248, 304688, 498209, 6317, 6318; Uniprot: P29508, P48594 |
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| Catalog # | PA5-75841 |
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| Price | |
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| Order / More Info | SERPINB3/SERPINB4 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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