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| Product Name | p21CIP1 Recombinant protein |
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| Description | MW: ~46 kDa. Purity >80%. Recombinant full-length human p21CIP1 was expressed in E. coli cells using a N-terminal GST tag.Scientific Background: CIP 1 (Cyclin-Dependent Kinase Inhibitor 1A) regulates cell cycle progression, terminal differentiation, and apoptosis (1). CIP1 was shown to be induced by p53 and to be a potent inhibitor of cyclin-dependent kinase (CDK) activity. DNA damage leads to increased expression of CIP1 in cyclin E-containing complexes and to an associated decre |
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| Size | 0.02 mg, 0.05 mg |
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| Concentration | 0.2 ug/ul |
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| Applications | Kinase Assay, Western Blot (WB) |
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| Other Names | [CDKN1A; P21; SDI1; WAF1; CAP20; CDKN1; MDA-6] |
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| Gene, Accession, CAS # | p21CIP1, Gene ID: 1026, Accession: NP_000380.1 |
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| Catalog # | MBS515251 |
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| Order / More Info | p21CIP1 Recombinant protein from MYBIOSOURCE INC. |
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| Product Specific References | 1. el-Deiry, W S. et al: WAF1/CIP1 is induced in p53-mediated G1 arrest and apoptosis. Cancer Res. 1994;54(5):1169-74 2. Wagner, M. et al: Cyclin-dependent kinase-inhibitor 1 (CDKN1A) in the squamous epithelium of the oropharynx: possible implications of molecular biology and compartmentation. Anticancer Res. 2001; 21(1A):333-45. |
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