| 产品详情 |
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| Product Name | LB 42708 |
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| Description | A potent inhibitor of FTase, blocking farnesylation of H-Ras, N-Ras, and K-Ras4B with IC50 values of 0.8, 1.2, and 2.0 nM, respectively; displays over 50,000-fold selectivity for FTase over geranylgeranyltransferase I |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | intracellular signaling angiogenesis cancer inflammation arthritis biochemical inhibit inhibitor faresylation post-translational addition 15-carbon isoprenyl protein Ras LB42708 farnesyltransferase farnesyl transferase FTase H-Ras N-Ras K-Ras-4B LPS IFN-γ activations NF-κB NFκB downstream RAW 264.7 RAW264.7 mouse macrophage mice Ras-dependent endothelial cell VEGF-mediated in vitro in vivo IFNγ HRas NRas KRas KRas4B protein lipidation |
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| Gene, Accession, CAS # | CAS: 226929-39-1 |
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| Catalog # | 16428-10 |
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| Order / More Info | LB 42708 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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