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| Product Name | PHLPP2 Recombinant protein |
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| Description | 766-1043. MW: ~ 56 kDa. Recombinant human PHLPP2 (766-1043) was expressed in E. coli cells using an N-terminal GST tag.Scientific Background: PHLPP2 or PH domain and leucine rich repeat protein phosphatase 2 is the important regulators of Akt serine-threonine kinases and conventional/novel protein kinase C (PKC) isoforms. PHLPP1 and PHLPP2 differentially regulated AKT signaling by selectively dephosphorylating the hydrophobic motifs of AKT2 or AKT3. PHLPP may act as a tumor suppre |
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| Size | 0.02 mg, 0.05 mg |
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| Concentration | n/a |
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| Applications | Phosphatase Assay, Western Blot (WB) |
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| Other Names | [KIAA0931; PHLPPL] |
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| Gene, Accession, CAS # | PHLPP2, Gene ID: 23035, Accession: NP_055835.2 |
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| Catalog # | MBS515171 |
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| Order / More Info | PHLPP2 Recombinant protein from MYBIOSOURCE INC. |
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| Product Specific References | 1. Brognard, J. et.al: PHLPP and a second isoform, PHLPp2, differentially attenuate the amplitude of Akt signaling by regulating distinct Akt isoforms. Molec. Cell 25: 917-931, 2007 |
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