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Product Name | Colistin Sulfate (Mixture of A and B compound) |
Description | Purity ~98%; Biological Potency (dry basis): 19600U/mg. Cyclic polypeptide antibiotic produced by Bacillus polymyxa. Complex mixture of at least 30 components, primarily colistin A and B. Colistin (polymyxin E) is a polymyxin antibiotic produced by certain strains of Bacillus polymyxa var. colistinus. Colistin is a mixture of cyclic polypeptides colistin A and B. Colistin is effective against most Gram-negative bacilli and is used as a polypeptide antibiotic. Colistin is a decades-old drug that fell out of favor due to its nephrotoxicity. It remains one of the last-resort antibiotics for multidrug-resistant Pseudomonas aeruginosa, Klebsiella pneumoniae, and Acinetobacter.[1] New Delhi metallo-β-Lactamase multidrug-resistant Enterobacteriaceae have also shown susceptibility to Colistin.[2] Colistin is polycationic and has both hydrophilic and lipophilic moieties. These poly-cationic regions interact with the bacterial outer membrane, by displacing bacterial counter ions in the lipo |
Size | 1g, 5g, 10g |
Concentration | n/a |
Applications | n/a |
Other Names | Polymyxin E. sulfate; Belcomycine; Colomycin |
Gene, Accession, CAS # | n/a |
Catalog # | C7509 |
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Order / More Info | Colistin Sulfate (Mixture of A and B compound) from UNITED STATES BIOLOGICAL |
Product Specific References | n/a |
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