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Product Name | BAFF Receptor, Recombinant, Human |
Description | Purity ~95% (SDS-PAGE and HPLC). BAFF Receptor (BAFFR), a member of the TNFR superfamily, is highly expressed in spleen, lymph node, and resting B cells and to some extent in activated B cells, resting CD4+ cells and peripheral blood leukocytes. BAFFR is a type III transmembrane protein that binds with high specificity to BAFF (TNFSF13B). BAFFR/BAFF signaling plays a critical role in B cell survival and maturation. Recombinant human BAFFR is a 76aa polypeptide (7.7kD) corresponding to the extracellular portion of the full BAFFR protein. Source: Recombinant protein corresponding to human BAFF Receptor, expressed in E.coli. Biological Activity: Determined by its ability to block BAFF induced mouse splenocyte survival. The expected ED50 for this effect is 2-4ug/ml in the presence of 1ug/ml of human soluble BAFF. Endotoxin: <0.1ng/ug (1EU/ug) AA Sequence: MRRGPRSLRG RDAPAPTPCV PAECFDLLVR HCVACGLLRT PRPKPAGASS PAPRTALQPQ ESVGAGAGEA ALPLPG |
Size | 10ug, 50ug |
Concentration | n/a |
Applications | n/a |
Other Names | BAFF Receptor, Recombinant, Human (BAFFR, BAFF-R, B Cell-activating Factor Receptor, BLyS Receptor 3, BR3, BROMIX, CD268, CVID4, MGC138235, Prolixin, Tumor Necrosis Factor Receptor Superfamily Member 13C, TNFRSF13C) |
Gene, Accession, CAS # | n/a |
Catalog # | 149654 |
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Order / More Info | BAFF Receptor, Recombinant, Human from UNITED STATES BIOLOGICAL |
Product Specific References | n/a |
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