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| Product Name | BAFF Receptor, Recombinant, Human (BAFFR, TNFRSF13C) |
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| Description | Purity ≥95% by SDS-PAGE gel and HPLC analyses. BAFF Receptor (BAFFR), a member of the TNFR superfamily, is highly expressed in spleen, lymph node, and resting B cells and to some extent in activated B cells, resting CD4+ cells and peripheral blood leukocytes.BAFFR is a type III transmembrane protein that binds with high specificity to BAFF (TNFSF13B).BAFFR/BAFF signaling plays a critical role in B cell survival and maturation.Recombinant human BAFFR is a 76 amino acid polypeptide (7.7kD) corresponding to the extracellular portion of the full BAFFR protein. Biological Activity: Determined by its ability to block BAFF induced mouse splenocyte survival. The expected ED50 for this effect is 2.0-4.0ug/ml in the presence of 1ug/ml of human soluble BAFF. AA Sequence: MRRGPRSLRGRDAPAPTPCVPAECFDLLVRHCVACGLLRTPRPKPAGASSPAPRTALQPQESVGAGAGEAALPLPG Crossreactivity: Mouse Quality Control: Verified by N-terminal and Mass Spectrometry analyses (when applicable). Endotoxin: <0.1ng/ug of protein (<1EU/u |
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| Size | 10ug, 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 143287 |
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| Order / More Info | BAFF Receptor, Recombinant, Human (BAFFR, TNFRSF13C) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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