| 产品详情 |
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| Product Name | SU 11274 |
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| Description | MW: 568.09. Purity ≥98% by HPLC. Background: A specific, ATP-competitive small molecule inhibitor of the catalytic activity of Met. Displays selectivity for Met enzyme versus a panel of other tyrosine kinases with the following IC?? values: Met = 0.02 muM, Flk = 1.3 muM, EGFR = >100 muM, PDGFbetaR = >20 muM, Tie2 = >100 muM, c-src = >10 muM, cdk2 = >10 muM, and FGFR-1 = 9.7 muM). Inhibition of the Met kinase activity by SU11274 leads to time- and dose-dependent reduced cell growth and induced |
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| Size | 5 mg, 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [3Z)-N-(3-Chlorophenyl)-3-({3,5-dimethyl-4-[(4-methylpiperazin-1-yl)carbonyl]-1H-pyrrol-2-yl}methylene)-N-methyl-2-oxo-2,3-dihydro-1H-indole-5-sulfonamide] |
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| Gene, Accession, CAS # | CAS: 658084-23-2 |
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| Catalog # | MBS841950 |
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| Price | |
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| Order / More Info | SU 11274 from MYBIOSOURCE INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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