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| Product Name | 4-1BB ligand, 71-254aa, Human, His tag, E Coli |
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| Description | MW: 23.8 kDa (222aa), confirmed by MALDI-TOF. Purity >95% by SDS-PAGE. 4-1BB ligand is a type 2 transmembrane glycoprotein belonging to the TNF superfamily. 4-1BBL is expressed by activated B cells, macrophages, dendritic cells, activated T cells, neurons and astrocytes. The interaction of 4-1BB with 4-1BBL strongly regulates immunity and has been proposed to preferentially control T cell responses based on studies in various murine models of cancer, infectious disease and autoimmune disease. Re |
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| Size | 0.1 mg, 0.5 mg |
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| Concentration | 1 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [Tumor necrosis factor ligand superfamily member 9; TNFSF9; 4-1BBL; CD137L; 4-1BB ligand; 4 1BB L; 4 1BB ligand; 4 1BBL; Cd137l; Cd157l; homolog of mouse 4 1BB L; homolog of mouse 4 1BBL; ILA ligand (TNF related); Ly63l; receptor 4 1BB ligand; Tumor necrosis factor (ligand) superfamily member 9.] |
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| Gene, Accession, CAS # | 4-1BB, Gene ID: 8744, Accession: NP_003802 |
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| Catalog # | MBS203312 |
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| Order / More Info | 4-1BB ligand, 71-254aa, Human, His tag, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Lee SW., et al. (2008). Nat Immunol. 9 (8):917-26; Sharma RK., et al. (2009). Cancer Res. 69 (10):4319-26; |
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