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Product Name | NU 7026 |
Description | ATP-competitive inhibitor of DNA-dependent protein kinase (DNA-PK). Displays selectivity over other PIKK family enzymes (IC50 values are 0.23, 13.0, > 100 and > 100 μM for DNA-PK, PI3K, ATM and ATR respectively). Radiosensitizes both proliferating and quiescent mouse embryonic fibroblast cells to IR and inhibits DSB repair. Purity 98%. MW (observed): 281.31 |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 2-(4-Morpholinyl)-4H-naphthol[1,2-b]pyran-4-one |
Gene, Accession, CAS # | CAS: 154447-35-5 |
Catalog # | 2828/10 |
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Order / More Info | NU 7026 from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 21552324, 22173583, 22334513, 22854598, 23253910, 23536727, 24247150, 25275444, 25625798, 25717108, 26437452, 26697402, 26716839 |
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