| 产品详情 |
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| Product Name | NU 6140 |
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| Description | Cyclin-dependent kinase 2 (cdk2) inhibitor (IC50 values are 0.42 - 1.1 μM). Displays some selectivity for cdk2 (IC50 value = 0.94 μM for cdk4 and >2.3 μM for other cdks). Induces cell-cycle arrest at the G2-M phase. Potentiates the apoptotic effect of taxol (Cat. No. 1097) in HeLa cells; down-regulates the antiapoptotic protein survivin. Also potently inhibits aurora kinases (IC50 values are 0.035 and 0.067 μM for aurora kinase B and A, respectively). Purity 99%. MW (observed): 422.52 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 4-[[6-(Cyclohexylmethoxy)-1H-purin-2-yl]amino]-N,N-diethylbenzamide |
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| Gene, Accession, CAS # | CAS: 444723-13-1 |
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| Catalog # | 3301/10 |
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| Price | |
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| Order / More Info | NU 6140 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 26882548, 27496804, 29170395 |
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| 产品资料 |
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