| 产品详情 |
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| Product Name | Canertinib (CI-1033, PD-183805) |
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| Description | MW: 558.86. Purity ≥99%. Background: Canertinib is an irreversible tyrosine kinase inhibitor. It not only inhibits tyrosine phosphorylation but also enhances ubiquitinylation and accelerates endocytosis and subsequent intracellular destruction of ErbB-2 molecules. Canertinib alkylates a cysteine residue specific to ErbB receptors. The degradative pathway of ErbB receptor tyrosine kinases stimulated by tyrosine kinase inhibitors appears to be chaperone mediated, and thus is similar to the path |
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| Size | 5 mg, 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [CI-1033; PD-183805; PD 183805] |
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| Gene, Accession, CAS # | CAS: 289499-45-2 |
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| Catalog # | MBS842036 |
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| Order / More Info | Canertinib (CI-1033, PD-183805) from MYBIOSOURCE INC. |
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| Product Specific References | n/a |
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