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| Product Name | Recombinant Human Twinkle protein, mitochondrial (PEO1) |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 75.5kDa. Full Length of Mature Protein: 32-684aa. N-terminal 6xHis-tagged. Homo sapiens (Human). Involved in mitochondrial DNA (mtDNA) metabolism. Could function as an adenine nucleotide-dependent DNA helicase. Function inferred to be critical for lifetime maintenance of mtDNA integrity. In vitro, forms in combination with POLG, a processive replication machinery, which can use double-stranded DNA (dsDNA) as tplate to synthesize single-stranded DNA (ssDNA) molecules. May be a key regulator of mtDNA copy number in mammals. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Progressive external ophthalmoplegia 1 protein; T7 gp4-like protein with intramitochondrial nucleoid localization; T7-like mitochondrial DNA helicase |
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| Gene, Accession, CAS # | PEO1, UniProt: Q96RR1 |
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| Catalog # | RPC25485 |
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| Order / More Info | Recombinant Human Twinkle protein, mitochondrial (PEO1) from BIOMATIK |
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| Product Specific References | n/a |
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