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| Product Name | Recombinant Human Interferon alpha/beta receptor 1 |
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| Description | 48-436aa; Extracellular Domain. MW: 74.2kD. Purity >90% as determined by SDS-PAGE. Associates with IFNAR2 to form the type I interferon receptor. Receptor for interferons alpha and beta. Binding to type I IFNs triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and IFNR alpha- and beta-subunits thselves. Can also transduce IFNB signals without the help of IFNAR2, and not activating the Jak-STAT pathway. |
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| Size | 0.01 mg (E-Coli), 0.05 mg (E-Coli), 0.1 mg (E-Coli), 0.2 mg (E-Coli), 0.5 mg (E-Coli) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Cytokine receptor class-II member 1; Cytokine receptor family 2 member 1; CRF2-1; Type I interferon receptor 1] |
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| Gene, Accession, CAS # | IFNAR1, Gene ID: 3454, Accession: NP_000620.2 |
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| Catalog # | MBS968510 |
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| Order / More Info | Recombinant Human Interferon alpha/beta receptor 1 from MYBIOSOURCE INC. |
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| Product Specific References | Genetic transfer of a functional human interferon alpha receptor into mouse cellscloning and expression of its cDNA.Uze G., Lutfalla G., Gresser I.Cell 60:225-234(1990) The structure of the human interferon alpha/beta receptor gene.Lutfalla G., Gardiner K., Proudhon D., Vielh E., Uze G.J. Biol. Chem. 267:2802-2809(1992) Complete sequencing and characterization of 21,243 full-length human cDNAs.Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Na |
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