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Product Name | Nogo-66 (1-40) |
Description | Peptide fragment corresponding to residues 1 - 40 of Nogo-66, the domain of the myelin protein Nogo that inhibits axonal outgrowth. Acts as a competitive antagonist at the Nogo-66 receptor (NgR); blocks Nogo-66- and CNS myelin-induced inhibition of axonal growth, but does not reduce myelin-associated glycoprotein (MAG) inhibition of neurite outgrowth in vitro. Promotes regeneration of hemisected spinal axons and locomotor recovery following spinal injury in vivo. MW (observed): 4625.16. |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | NEP1-40, Nogo Extracellular Peptide, 1-40 |
Gene, Accession, CAS # | CAS: 475221-20-6 |
Catalog # | 1984/1 |
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Order / More Info | Nogo-66 (1-40) from TOCRIS BIOSCIENCE
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Product Specific References | n/a |
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