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| Product Name | Human TIGAR |
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| Description | MW: 30,063 Da. Purity >95% by SDS-PAGE & HPLC analyses. TIGAR is a p53-inducible enzyme that catalyzes the hydrolysis of fructose-2-6 bisphosphate (F-2-6-BP) to fructose-6-phosphate and inorganic phosphate. F-2-6-BP is a powerful activator of 6-phosphofructose-1 kinase, the rate limiting enzyme of glycolysis. By lowering the intracellular level of F-2-6-BP, TIGAR expression leads to increased glucose processing via the pentose phosphate pathway, the major cellular source for NADPH. Recombinant h |
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| Size | 0.005 mg, 0.025 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [TP53-induced glyclysis and apoptosis regulator] |
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| Gene, Accession, CAS # | TIGAR , Gene ID: 57103, Accession: NP_065108.1 |
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| Catalog # | MBS691691 |
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| Price | |
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| Order / More Info | Human TIGAR from MYBIOSOURCE INC. |
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| Product Specific References | n/a |
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