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| Product Name | nth, 1-211aa, E Coli, His tag, E Coli |
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| Description | MW: 25.7 kDa (231aa) confirmed by MALDI-TOF. Purity >90% by SDS-PAGE. Endonuclease III, also known as nth, is a DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product w |
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| Size | 0.05 mg, 0.25 mg |
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| Concentration | 0.25 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [Endonuclease III; b1633; JW1625; DNA- (apurinic or apyrimidinic site) lyase; Endonuclease-III] |
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| Gene, Accession, CAS # | nth, Gene ID: 947122, Accession: NP_416150 |
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| Catalog # | MBS204028 |
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| Order / More Info | nth, 1-211aa, E Coli, His tag, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Cunningham R.P., et al. (1994) Acad. Sci. 726:215-222; Asahara H., et al. (1989) Biochemistry. 28:4444-4449 |
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