| 产品详情 |
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| Antigenic Specificity | ZIP1 (extracellular) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 50 µl |
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| Concentration | lyophilized |
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| Applications | Immunofluorescence: 1:400, Immunohistochemistry: 1:400, Western Blot: 1:200-1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | ZIP1 (extracellular) Polyclonal Antibody. ZIP1, also known as ZIRTL (zinc-iron regulated transporter-like), is the first mammalian member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP1 expression is markedly downregulated in a number of cancerous tissues and is thought to function as a tumor suppressor gene in prostate cancer. More recent studies have shown that overexpression of ZIP1 and concomitant increased levels of intracellular zinc in PC-3 cells cause a significant inhibition of NF-kappa-B, leading to down-regulation of the antiapoptotic protein Bcl-2, Bcl-XL, and the apoptosis inhibitor XIAP, reducing the malignant potenti |
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| Immunogen | n/a |
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| Other Names | Zinc transporter 1 ZIP1, Zinc/Iron Regulated Transporter-Like, SLC39A1 |
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| Gene, Accession # | Entrez: 27173, 30791, 361986; Uniprot: Q9NY26, Q9QZ03 |
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| Catalog # | PA5-77766 |
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| Price | |
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| Order / More Info | ZIP1 (extracellular) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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