| 产品详情 |
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| Product Name | Gliclazide |
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| Description | A sulfonylurea and an inhibitor of pancreatic β-cell KATP channels (IC50 = 184 nM for murine β-cells); selective for pancreatic β-cell over cardiac and arterial smooth muscle cell KATP channels (IC50s = 19.5 and 37.9 µM, respectively); increases insulin-induced glucose uptake and GLUT4 translocation to the plasma membrane in a differentiated 3T3L1 adipocyte model of insulin resistance induced by hydrogen peroxide at 5 µM; reduces LDL oxidation by HASMCs, decreasing TBARS content and 8-isoprostane levels at 5 and 10 µg/ml; decreases oxidized LDL-induced HASMC proliferation and monocyte adhesion at 1-10 µg/ml; reduces serum glucose levels and increases glucose uptake by isolated rat hindquarters in a model of diabetes induced by STZ at 5mg/kg |
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| Size | 1 g |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Diabezidum Diabrezide Diabyl Diaprel Glimicron Glinormax Glyzide 1702 S 852 SE GLUT 4 3T3 L1 low density lipoprotein S1702 S852 SE1702 Diamicron |
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| Gene, Accession, CAS # | CAS: 21187-98-4 |
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| Catalog # | 25503-1 |
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| Price | |
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| Order / More Info | Gliclazide from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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