| 产品详情 |
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| Antigenic Specificity | RNF19A |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | peptide affinity purified |
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| Size | 80 µl, 400 µl |
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| Concentration | n/a |
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| Applications | WB, IHC. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | The protein encoded this gene contains two RING-finger motifs and an IBR (in between RING fingers) motif. This protein is an E3 ubiquintin ligase that is localized in Lewy bodies (LBs), a characteristic neuronal inclusion in Parkinson's disease (PD) brains. This protein interacts with UBE2L3/UBCH7 and UBE2E2/UBCH8, but not other ubiquitin-conjugating enzymes. This protein is found to bind and ubiquitylate synphilin 1 (SNCAIP), which is a interacting protein of alpha synuclein in neurons, and a major component of LB. Alternatively spliced transcript variants encoding the same protein have been reported. This RNF19A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 384-413 amino acids from the Central region of human RNF19A. |
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| Immunogen | Human RNF19A. |
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| Other Names | RNF19A; DORFIN; Double ring-finger protein; RING finger protein 19 isoform; RNF19; Ring finger protein 19; p38; p38 protein; RING finger protein 19A; E3 ubiquitin-protein ligase RNF19A |
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| Gene, Accession # | RNF19A, SwissProt: Q9NV58 |
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| Catalog # | abx027899 |
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| Price | |
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| Order / More Info | RNF19A Antibody from ABBEXA |
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| Product Specific References | n/a |
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