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| Antigenic Specificity | Melanoma Antigen Family D, 1 (MAGED1) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | mouse, rat, human |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 50 µg |
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| Concentration | n/a |
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| Applications | Western Blotting (WB),Immunohistochemistry (IHC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | MAGE-D1, also known as NRAGE or Dlxin-1, is a member of the MAGE family of proteins. Identified as a p75 neurotrophin receptor intracellular binding protein, MAGE-D1 induces developmental apoptosis of motoneurons, and is required for p75NTR-dependent apoptosis in sympathetic neurons. It is suggested that MAGE-D1 can suppress the motility and adhesion response of tumor cells. By forming a hetercomplex with Dlx/Msx family homeodomain proteins and Necdin, MAGE-D1 modulates the function of Dlx/Msx homeodomain during terminal differentiation and maturation of neurons. MAGE-D1 is also involved in the phosphorylation of IKK-alpha/beta, and subsequent transcriptional activation of the p65 subunit of NF-kappaB, via the XIAP-Tak1-Tab1 complex. (20100315, 19639218, 17453828, 15272023) G. Synonyms: MAGED1,DLXIN-1,NRAGE , |
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| Immunogen | Recombinant protein of human MAGED1 |
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| Other Names | MAGED1|DLXIN-1|NRAGE|2810433C11Rik|5430405L04Rik|DXBwg1492e|Dlixin|Dlxin-1|Dlxin1|MAGE-D1|mFLJ00163|Nrage |
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| Gene, Accession # | Gene ID: 9500,94275,84469 |
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| Catalog # | ABIN1683751 |
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| Price | |
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| Order / More Info | Melanoma Antigen Family D, 1 (MAGED1) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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