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| Product Name | NEu1, 48-415aa, Human, His tag, E Coli |
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| Description | MW: 42.9 kDa (393aa), confirmed by MALDI-TOF. Purity >85% by SDS-PAGE. NEu1 is a lysosomal enzyme that cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A. Mutations in this gene can lead to sialidosis, a lysosomal storage disease that can be type 1 (cherry red -myoclonus syndrome or normosomatic type), which is late-onset, or type 2 (the dysm |
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| Size | 0.1 mg, 0.5 mg |
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| Concentration | 0.25 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [Sialidase 1 (lysosomal sialidase); NANH; NEu; SIAL1] |
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| Gene, Accession, CAS # | NEu1, Gene ID: 4758, Accession: NP_000425 |
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| Catalog # | MBS204313 |
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| Order / More Info | NEu1, 48-415aa, Human, His tag, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Abdulkhalek,S., et al. (2011) J. Biol. Chem. 286 (42), 36532-36549 |
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