| 产品详情 |
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| Product Name | SNS 032 |
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| Description | Cyclin dependent kinase (cdk) inhibitor (reported IC50 values are 0.004 - 0.048, 0.0045 - 0.05, 0.062 - 0.29, 0.2-0.48, 0.4 and 0.45 μM for cdk9, cdk2, cdk7, cdk1, cdk5 and cdk4, respectively). Displays no activity against 190 additional kinases (IC50 >1 μM). Arrests the cell cycle at G2/M; inhibits transcription, proliferation and colony formation, and induces apoptosis in RPMI-8226 multiple myeloma cells. Prevents tumor cell-induced VEGF secretion and in vitro angiogenesis. Purity 99%. MW (observed): 380.53 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-[5-[[[5-(1,1-Dimethylethyl)-2-oxazolyl]methyl]thio]-2-thiazolyl]-4-piperidinecarboxamide. BMS-387032 |
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| Gene, Accession, CAS # | CAS: 345627-80-7 |
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| Catalog # | 4075/10 |
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| Price | |
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| Order / More Info | SNS 032 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 25673708 |
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| 产品资料 |
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