| 产品详情 |
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| Product Name | UMI-77 |
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| Description | UMI-77 is a novel, selective, Mcl-1 SMI inhibitor. UMI-77 is selective for Mcl-1 over other members of the antiapoptotic Bcl-2 family with a Ki of 490 nM. UMI-77 acts by binding to the BH3-binding groove of Mcl-1, blocking the heterodimerization of Mcl-1/Bax and Mcl-1/Bak. It inhibits cell growth and induces apoptosis in pancreatic cancer cells. MW: 468.34. Purity ≥98% by HPLC |
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| Size | 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2-[4-[(4-bromophenyl)sulfonylamino]-1-hydroxynaphthalen-2-yl]sulfanylacetic acid |
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| Gene, Accession, CAS # | CAS: 518303-20-3 |
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| Catalog # | B1108-25 |
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| Order / More Info | UMI-77 from BIOVISION, INC. |
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| Product Specific References | n/a |
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