| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | TAB2 |
|---|
| Clone | G.188.0 |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human, mouse, nonhuman primate, rat |
|---|
| Isotype | IgG |
|---|
| Format | purified |
|---|
| Size | 100 µL |
|---|
| Concentration | n/a |
|---|
| Applications | Immunoprecipitation: 1:100, Western Blot: 1:1000 |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | TAB2 Monoclonal Antibody (G.188.0). The protein encoded by this gene is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, thus serves as an adaptor linking MAP3K7 and TRAF6. This protein, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts. |
|---|
| Immunogen | n/a |
|---|
| Other Names | OTTHUMP00000017388; TAB-2; TAK1-binding protein 2; TGF-beta-activated kinase 1 and MAP3K7-binding protein 2; TGF-beta-activated kinase 1-binding protein 2; mitogen-activated protein kinase kinase kinase 7-interacting protein 2 |
|---|
| Gene, Accession # | Entrez: 23118, 308267, 68652; Uniprot: Q5U303, Q99K90, Q9NYJ8 |
|---|
| Catalog # | MA5-14818 |
|---|
| Price | |
|---|
| Order / More Info | TAB2 Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|