| 产品详情 |
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| Antigenic Specificity | ASK1/MAPKKK5 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 100 µg |
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| Concentration | 0.2 mg/ml |
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| Applications | Western blot, Immunofluorescence |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | ASK1/MAPKKK5 Antibody. ASK1 (Apoptosis Signal-regulating Kinase 1) activates two different subgroups of MAPKK, MKK4 and MKK6, which in turn activate c-Jun N-terminal Kinase (JNK) and p38 MAP Kinase. ASK1 is activated by TNFR and Fas throµgh the interaction with members of the TRAF Family and the Fas-associated protein Daxx. Overexpression of ASK1 induces apoptosis. However, a catalytically inactive form of ASK1 has been shown to inhibit TNF-α induced apoptosis. |
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| Immunogen | Synthetic peptide corresponding to residue surrounding amino acid 1359 of human ASK1 |
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| Other Names | MAP3K5, MEKK5, ASK-1 , MAPKKK5 |
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| Gene, Accession # | Gene ID: 4217, Accession: Q99683 |
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| Catalog # | 3128-100 |
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| Price | |
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| Order / More Info | ASK1/MAPKKK5 Antibody from BIOVISION, INC. |
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| Product Specific References | n/a |
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