| 产品详情 |
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| Antigenic Specificity | Phospho-ASK1 (Ser83) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | WB, ELISA, IHC |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Polyclonal antibody to detect endogenous levels of ASK 1 protein only when phosphorylated at S83 in human. ASK1 (Apoptosis Signal-regulating Kinase 1) activates two different subgroups of MAPKK, MKK4 and MKK6, which in turn activate c-Jun N-terminal Kinase (JNK) and p38 MAP Kinase. ASK1 is activated by TNFR and Fas through the interaction with members of the TRAF Family and the Fas-associated protein Daxx. Overexpression of ASK1 induces apoptosis. However, a catalytically inactive form of ASK1 has been shown to inhibit TNF-α induced apoptosis. |
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| Immunogen | Synthesized peptide derived from human ASK 1 around the phosphorylation site of S83, (20-100aa) |
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| Other Names | Mitogen-activated protein kinase kinase kinase 5, Apoptosis signal-regulating kinase 1, MAPK/ERK kinase kinase 5, MEK kinase 5, MEKK 5 |
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| Gene, Accession # | Gene ID: 4217, Accession: Q99683 |
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| Catalog # | A1241-100 |
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| Price | |
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| Order / More Info | Phospho-ASK1 (Ser83) Antibody from BIOVISION, INC. |
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| Product Specific References | n/a |
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