| 产品详情 |
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| Antigenic Specificity | TAK1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | Protein A purified |
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| Size | 100ug |
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| Concentration | 0.5-1mg/ml, actual concentration varies by lot. |
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| Applications | IHC |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit Anti-TAK1 Antibody for Map3k7 detectiontested for IHC in Human, Mouse, Rat. Mitogen-activated protein kinase kinase kinase 7, also known as TAK1, is an enzyme that in humans is encoded by the MAP3K7 gene. The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. |
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| Immunogen | Synthetic peptide corresponding to a portion of mouse TAK1. |
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| Other Names | Mitogen-activated protein kinase kinase kinase 7;2.7.11.25;Transforming growth factor-beta-activated kinase 1;TGF-beta-activated kinase 1;Map3k7;Tak1; |
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| Gene, Accession # | Map3k7, UniProt: Q62073 |
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| Catalog # | A01458 |
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| Price | |
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| Order / More Info | TAK1 Antibody from BOSTER BIO |
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| Product Specific References | n/a |
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