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| Antigenic Specificity | Human TAK1 (phospho Thr184, Thr187) |
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| Clone | L.957.4 |
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| Host Species | Rabbit |
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| Reactive Species | bovine, chicken, human, mouse, rat, Xenopus, zebrafish |
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| Isotype | IgG |
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| Format | unconjugated |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit Anti-Human TAK1 (phospho Thr184, Thr187) monoclonal antibody for WB. The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/NhpK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. |
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| Immunogen | Phosphopeptide corresponding to residues surrounding pThr184 and pThr187 of human TAK1 |
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| Other Names | n/a |
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| Gene, Accession # | Gene ID: 6885, UniProt: O43318 |
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| Catalog # | CABT-L1458 |
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| Price | |
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| Order / More Info | Human TAK1 (phospho Thr184, Thr187) Antibody from CREATIVE DIAGNOSTICS |
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| Product Specific References | n/a |
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