| 产品详情 |
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| Antigenic Specificity | TLR9, aa204-224 |
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| Clone | polyclonal |
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| Host Species | Goat |
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| Reactive Species | mouse, hamster, human |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | IHC, IHC-P (1:250), WB (1:1000) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | TLR9 Antibody (aa204-224) LS-C187710. Recognizes murine Toll-like receptor 9, also known as CD289 or TLR9. CD289 is an 1032 amino acid ~120 kD endosomal single pass type I transmembrane glycoprotein with a number of and a single domain. Recognizes an epitope within the N-terminal (NT) region of CD289, a member of the toll-like receptor family, which triggers MyD88 and TRAF6, resulting in NF-kappaB activation, cytokine secretion and the inflammatory response. CD289 acts as a receptor for unmethylated cytidine-phosphate-guanosine dinucleotides in bacterial DNA (CpG-DNA), playing a primary role in pathogen recognition and activation of innate immunity and has been shown to play a role in defense against systemic mouse cytomegalovirus infection. Is reported as suitable for use in immunocytochemistry on acetone fixed cells. |
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| Immunogen | Synthetic peptide LSLKYNNLTKVPRQLPPSLEY-C corresponding to amino acids 204-224 within the N-terminal region of mouse CD289. Percent identity by BLAST analysis: Mouse, Hamster (100%); Rat (95%); Panda, Dog, Cat, Horse, Guinea pig (90%); Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Ferret, Elephant, Pig (86%); Sheep, Goat, Zebu, Bovine, Rabbit (81%). |
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| Other Names | TLR9, CD289, CD289 antigen, Scri2a, Toll-like receptor 9 |
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| Gene, Accession # | TLR9, Gene ID: 54106 |
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| Catalog # | LS-C187710 |
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| Price | |
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| Order / More Info | TLR9, aa204-224 Antibody from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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