| 产品详情 |
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| Product Name | Imatinib Mesylate (CGP-57148B, STI-571) |
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| Description | An inhibitor of the bcr-abl tyrosine kinase. It acts by binding to the ATP binding site of bcr-abl. Imatinib also stimulates the entry of the bcr-abl tyrosine kinase into the nucleus, where it cannot perform its anti-apoptopic functions. It inhibits EOL-1 cell viability (IC50 = 0.5 nM), phosphorylation of a fusion protein (IC50 = 30 nM), and viability of BaF3 cells expressing Rhe-PDGFRα in the absence of IL-3 (IC50 = 0.17 nM). MW: 589.71. Purity ≥99% by HPLC |
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| Size | 1 g |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | CGP-57148B, STI-572 |
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| Gene, Accession, CAS # | CAS: 220127-57-1 |
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| Catalog # | 1625-1000 |
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| Order / More Info | Imatinib Mesylate (CGP-57148B, STI-571) from BIOVISION, INC. |
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| Product Specific References | n/a |
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