产品详情 |
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Antigenic Specificity | ZYX |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 50 µl, 100 µl, 200 µl |
Concentration | > 1 mg/ml |
Applications | WB. RUO |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ZYX Antibody is a Rabbit Polyclonal antibody against ZYX. Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform. |
Immunogen | Recombinant protein of human ZYX. |
Other Names | Zyxin; ZYX; ESP2; HED2 |
Gene, Accession # | ZYX, Gene ID: 7791, SwissProt: Q15942 |
Catalog # | abx001747 |
Price | |
Order / More Info | ZYX Antibody from ABBEXA |
Product Specific References | n/a |
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