产品详情 |
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Antigenic Specificity | PTPN18 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl |
Concentration | n/a |
Applications | WB. RUO |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, the mitotic cycle, and oncogenic transformation. This PTP contains a PEST motif, which often serves as a protein-protein interaction domain, and may be related to protein intracellular half-live. This protein can differentially dephosphorylate autophosphorylated tyrosine kinases that are overexpressed in tumor tissues, and it appears to regulate HER2, a member of the epidermal growth factor receptor family of receptor tyrosine kinases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]. This PTPN18 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 430-459 amino acids from the C-terminal region of human PTPN18. |
Immunogen | Human PTPN18. |
Other Names | protein tyrosine phosphatase; non-receptor type 18 (brain-derived); PTPN18; BDP1; PTP-HSCF; Tyrosine-protein phosphatase non-receptor type 18; Brain-derived phosphatase |
Gene, Accession # | PTPN18, SwissProt: Q99952 |
Catalog # | abx029158 |
Price | |
Order / More Info | PTPN18 Antibody from ABBEXA |
Product Specific References | n/a |
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