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| Product Name | CDA, 1-146aa, Human, His tag, E Coli (Bioactivity Validated) |
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| Description | MW: 18.3 kDa (166aa), confirmed by MALDI-TOF. Purity >90% by SDS-PAGE. CDA (Cytidine deaminase) is an enzyme that scavenges exogenous and endogenous cytidine and 2-deoxycytidine for uMP synthesis. This protein is one of several deaminases responsible for maintaining the cellular pyrimidine pool. The protein also catalyzes the deamination of chemotherapeutic cytosine nucleoside analogs such as Ara-C and 5-azacytidine, which results in the loss of their cytotoxic and antitumor function. It can for |
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| Size | 0.1 mg, 0.5 mg |
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| Concentration | 0.5 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [Cytidine deaminase; CDD; Cytidine aminohydrolase; Cytosine nucleoside deaminase; Cytidine deaminase] |
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| Gene, Accession, CAS # | CDA, Gene ID: 978, Accession: AAH54036 |
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| Catalog # | MBS203660 |
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| Order / More Info | CDA, 1-146aa, Human, His tag, E Coli (Bioactivity Validated) from MYBIOSOURCE INC. |
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| Product Specific References | Evrard A., et al. (2010) Ther Drug Monit. 32 (1):53-60.; Seeberg EC., et a/. (1998) Blood. 91 (11):4127-35.; |
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