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| Product Name | KRT8, 1-483aa, Human His tag, E.coli (Denatured) |
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| Description | Purity: > 90% by SDS - PAGE Format: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol . KRT8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. KRT8 typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Recombinant human KRT8 protein, fused to His-tag at N-terminus, was expressed in E.coli. |
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| Size | 0.5mg, 100ug, 20ug |
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| Concentration | n/a |
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| Applications | SDS-PAGE |
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| Other Names | Keratin type II cytoskeletal 8, Keratin, type II cytoskeletal 8, keratin 8, CARD2, CK-8, CK8, CYK8, K2C8, K8, KO |
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| Gene, Accession, CAS # | NP 002264 |
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| Catalog # | ATGP2076 |
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| Order / More Info | KRT8, 1-483aa, Human His tag, E.coli (Denatured) from ATGen |
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| Product Specific References | n/a |
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