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| Product Name | Crizotinib |
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| Description | Potent inhibitor of c-MET and anaplastic lymphoma kinase (ALK) (cell IC50 values are 8.0 and 20 nM respectively). Selective for c-MET and ALK against >120 different kinases. Displays antitumor efficacy in multiple tumor models; inhibits c-MET-dependent proliferation, migration and invasion of human tumor cells in vitro. Orally bioavailable. Purity 99%. MW (observed): 450.34 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 3-[(1R)-1-(2,6-Dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-2-pyridinamine. PF 02341066, PF 2341066 |
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| Gene, Accession, CAS # | CAS: 877399-52-5 |
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| Catalog # | 4368/10 |
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| Price | |
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| Order / More Info | Crizotinib from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 21266357, 22660439, 27109105, 29042798 |
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| 产品资料 |
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