| 产品详情 |
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| Antigenic Specificity | 14-3-3 zeta/delta |
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| Clone | W15121A |
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| Host Species | Rat |
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| Reactive Species | human, mouse, rat |
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| Isotype | IgG1, κ |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blot (WB), ICC |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Purified anti-14-3-3 ζ/δ. In mammals, proteins of the 14-3-3 family include isoforms β, γ, ε, σ, ζ, τ, and η. 14-3-3 δ isoform is the phosphorylated form of 14-3-3 ζ. These highly conserved proteins form homo- or heterodimers with many transcription factors, metabolic enzymes, kinases, phosphatases, and other signaling molecules, generally through a phospho-Ser/Thr motif. The binding regulates the location, stability, interaction with other molecules, and phosphorylation status of the target proteins which suggests the important roles for these 14-3-3 family proteins on regulation of cellular functions and responses. Growing data demonstrate that the specific temporal and spatial distributions of 14-3-3 family proteins are critical for developmental processes; and in some cancers, the regulation of these proteins are different from healthy controls. 14-3-3 ζ interacts with IRS1 protein and is involved in the PI3K-Akt signaling pathway. |
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| Immunogen | Full length human 14-3-3 ζ/δ recombinant protein expressed in E. coli. |
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| Other Names | Protein kinase C inhibitor protein 1, KCIP-1, HEL4, YWHAD, HEL-S-3, HEL-S-93, 14-3-3-zeta |
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| Gene, Accession # | Gene ID: 7534 |
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| Catalog # | 687802 |
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| Price | |
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| Order / More Info | 14-3-3 zeta/delta Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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