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| Product Name | CRKL, 1-303aa, Human, His tag, E Coli |
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| Description | MW: 35.9 kDa (323aa), confirmed by MALDI-TOF. Purity >90% by SDS-PAGE. CRKL is a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JuN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substitutete of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and has oncogenic potential. Recombinant human CRKL protein, fused to His-tag at N-terminus, was expressed in E Coli and p |
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| Size | 0.1 mg, 0.5 mg |
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| Concentration | 1 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [Crk-like protein] |
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| Gene, Accession, CAS # | CRKL, Gene ID: 1399, Accession: NP_005198 |
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| Catalog # | MBS203760 |
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| Order / More Info | CRKL, 1-303aa, Human, His tag, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Arai A., et al. (2001) J Biol Chem. 276 (35):33282-90. ; Senechal K., et al. (1996) J Biol Chem. 271 (38):23255-61.; |
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