| 产品详情 |
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| Antigenic Specificity | mab27 |
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| Clone | i 127 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgE |
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| Format | purified |
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| Size | 100µg/50µg |
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| Concentration | n/a |
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| Applications | MACS-separation & FACS |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Cell surface receptors for the Fc fragments of IgE (FceR) have been identified on a variety of cell types from hematopoietic origin. The low affinity receptor for IgE (CD23) has been described as a B cell-activation marker. IgE-binding factors have been shown to play a major role in the regulation of IgE production. Basophils and mast cells express FceR1, which bind IgE with high affinity and the reaction of allergen with cell-bound IgE induces the release of a variety of pharmacologically active mediators that are responsible for the clinical manifestations of allergic disorders. mAb27 was generated from a mouse immunization program aiming at producing mAb specific for human IgE-Fc in order to map the sites on IgE interacting with receptors on target cells. (Chretien I. et al, J. Immunol, 1988, (9) 141, pp3128-34). |
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| Immunogen | n/a |
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| Other Names | n/a |
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| Gene, Accession # | n/a |
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| Catalog # | DDX0290 |
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| Price | |
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| Order / More Info | mab27 Antibody from DENDRITICS SAS |
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| Product Specific References | n/a |
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